Israel’s Nectin Therapeutics (see here previously) has started human trials of its NTX1088 cancer treatment. NTX1088 blocks the protein PVR expressed by tumors to suppress the immune system. The treatment also restores DNAM-1, needed to activate anti-cancer T & NK … Continue reading →

Many tumors express the protein PD-L1, which allows them to circumvent the immune system. Scientists at Israel’s Technion Institute have developed neural networks that use “deep learning” AI to recognize PD-L1 in biopsies, alerting oncologists to apply appropriate immunotherapy. https://www.technion.ac.il/en/2022/11/deep-learning-breast-cancer-ai-immunotherapy/

Scientists from Israel’s Technion Institute and Sheba Medical Center have discovered that proteins in lung fluid, known as HLA peptides, store information that can detect types of lung cancer. The HLA molecules contain antigens that can stimulate the immune system … Continue reading →

Israel’s NeoTX (see here previously) is now conducting a Phase 2 trial of its naptumomab estafenatox (NAP) bacteria-coated, immunotherapy cancer treatment on 30 patients in the US. It is also enhancing an AstraZeneca checkpoint inhibitor. NeoTX has 3 Nobel prizewinners … Continue reading →

MesenCure – the life-saving Covid-19 treatment from Israel’s Bonus BioGroup (see here) also prevents a lethal inflammatory response that affects cancer patients receiving immunotherapy. In California trials MesenCure significantly reduced an overreaction of the immune system. https://worldisraelnews.com/israeli-covid-drug-also-aids-cancer-immunotherapy-patients/

Researchers at Tel Aviv University have developed a 2-in-1 anti-cancer nanoparticle. It is the world’ first RNA-based treatment to combine chemotherapy to destroy cancer cells and immunotherapy to stimulate the immune system to identify and attack the remaining cancer cells. … Continue reading →

Scientists at Israel’s Weizmann Institute have improved a cancer therapy that killed tumors but was too toxic for use.  They added a specially created antibody that targets only the CD40 receptor protein molecule which stimulates the immune system to fight … Continue reading →

Scientists at Israel’s Weizmann Institute have discovered that in addition to cancer-fighting T-cells, the immune system’s B-lymphocytes also produce antibodies that take part in battles against cancer cells. They target the enzyme MMP14, a cause of metastasis and can be … Continue reading →

An Israeli-led team of scientists have developed a blood test that analyzes fragments of DNA to determine the impact of the immune system. The test is like a liquid biopsy and can detect cancer early in remote tissues, e.g., bone … Continue reading →

Researchers at Tel Aviv University have discovered that a type of white blood cell (eosinophils) can be utilized to fight cancer. They have a double effect, producing destructive proteins, while at the same time summoning the immune system’s cancer-fighting T-cells. … Continue reading →