Scientists at Israel’s Bar-Ilan University, working with Canadian scientists have developed peptides (small proteins) that in laboratory tests prevent the production of oligomers – small polymers that are the true culprits of the neuron damage in Alzheimer’s disease. https://www.israel21c.org/treatment-for-very-early-alzheimers-under-development/ https://www.pnas.org/doi/10.1073/pnas.2210766119

In 2023, Bar-Ilan University Prof Shai Rahimipour (see here previously) worked with Canadian scientists on a peptide therapy for Alzheimer’s disease. Now he is working with Italian scientists developing nanoparticles to attack an early version of the Amyloid-beta protein. https://tps.co.il/articles/nanotechnology-breakthrough-could-transform-alzheimers-care/

Israeli biotech MemoryPlus has developed a peptide to block the interaction of proteins PTEN & PSD-95, that causes memory loss in Alzheimer’s patients. The disease makes excessive PTEN, which attacks PSD-95, weakening the brain’s synapses. The peptide also lowers PTEN … Continue reading →

High blood sugar levels in diabetics produce more enzymes called MAPK kinases, leading to early brain cell death. Hebrew University of Jerusalem researchers have developed a peptide TXM-CB3 that in laboratory tests prevents the MAPK kinases from activating. http://www.eurekalert.org/pub_releases/2014-01/thuo-nmp012814.php

(Thanks to NoCamels.com) Professor Illana Gozes of Tel Aviv University has created a new peptide (short protein) called NAP that latest trials indicate could treat neuro-degenerative diseases such as Alzheimer’s, ALS or Parkinson’s. http://nocamels.com/2013/07/new-study-may-may-help-lead-the-way-to-treatment-for-neurodegenerative-diseases/

Tel Aviv University scientists have made progress in developing a treatment using the NAP peptide to counter Alzheimer’s and other neurological conditions (see here previously). Their new compound dramatically decreased the excessive buildup of the protein tau, which misfolds in … Continue reading →

In her lab, Professor Illana Gozes of Tel Aviv University (reported here previously) repaired live but damaged brain cells taken from deceased Alzheimer’s patients and an autistic child. It showed that her experimental NAP peptide could be used to treat … Continue reading →

Israeli scientists have developed half-a-dozen proteins to treat either inflammatory diseases (see here and here) or neuro-degenerative diseases (here and here) But the 5-mer peptide, developed by Professor David Naor of the Hebrew University of Jerusalem, treats them all. https://www.israel21c.org/one-drug-could-treat-alzheimers-ms-crohns-and-more/

I reported previously (Feb 2014) about Hebrew University of Jerusalem scientists’ development of TXM peptides that can reduce the risk of Alzheimer’s and dementia in diabetics.  Latest HUJ research shows that TXM peptides can also protect the brain after mild … Continue reading →