Targeting a cause of ALS

Scientists at Tel Aviv University have developed an experimental molecule that breaks down the protein TDP-43, a key cause of ALS (Lou Gehrig’s disease). TDP-43 causes motor neurons to degenerate. The new molecule enabled motor neuron activity to be restored and opens the door to an ALS cure.

https://www.timesofisrael.com/tel-aviv-university-breakthrough-touted-as-key-to-reversing-als/

https://www.nature.com/articles/s41467-021-27221-8#Sec46

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