Hebrew University researchers have developed a chip containing human tissue with microscopic sensors to precisely monitor the response of the kidney, liver and heart to specific treatments. It is believed to be the first treatment to be submitted to the US FDA for human trials without animal testing.

https://www.timesofisrael.com/israelis-create-cancer-drug-using-human-simulating-chip-instead-of-animal-tests/

https://stm.sciencemag.org/content/13/582/eabd6299