Researchers at Israel’s Technion have developed nanotechnology that replaces the dentist’s scalpel with the target release of the enzyme collagenase to break down collagen fibers in the gums. It spares the pain associated with orthodontic surgeries and significantly reduces tissue recovery time.

https://www.technion.ac.il/en/2018/02/orthodontic-surgery-with-an-enzymatic-blade-no-incision-necessary/

http://www.jpost.com/HEALTH-SCIENCE/New-Israeli-technology-replaces-surgeons-knife-with-no-cut-alternative-542769

https://pubs.acs.org/doi/abs/10.1021/acsnano.7b07983