Protein discovered in cancer that fools immune system

A team led by Weizmann scientists has discovered that the protein PSME4 is produced by cancer cells to stop the immune system from attacking the tumor. Reducing PSME4 levels should potentially render tumors more vulnerable to immunotherapy.

https://www.jns.org/israeli-researchers-unmask-how-cancer-camouflages-itself/

https://wis-wander.weizmann.ac.il/life-sciences/dumpster-diving-cancer-tissue-uncovers-immune-evasion-mechanism

https://www.nature.com/articles/s43018-023-00557-4

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