Dr Waldemar Haffkine, a Russian-Jewish microbiologist, developed the cholera vaccine in 1892.  Jerusalem’s Tower of David Museum is now exhibiting one of the original ampoules of vaccine.  Dr Haffkine also developed a vaccine for plague and was knighted by Queen Victoria in 1897.  Sir Waldemar donated his extensive personal archive to the National Library of Israel.

http://www.timesofisrael.com/original-cholera-vaccine-turns-up-in-jerusalem/