Scientists at Israel’s Weizmann Institute have identified two small molecules capable, in the laboratory, of penetrating the blood-brain barrier and reducing the levels of a defective protein that causes Huntington’s disease.
https://www.jns.org/israeli-researchers-take-step-toward-cure-for-huntingtons-disease/
https://wis-wander.weizmann.ac.il/life-sciences/toward-treatment-huntington%E2%80%99s-disease
https://www.embopress.org/doi/full/10.1038/s44321-023-00020-y