Scientists in Israel, China and Singapore have discovered a molecule 3,3′-Diindolylmethane (DIM – also known as bisindole) reduces the biofilms that produce dental plaque and cavities by 90%. The molecule is also found to have anti-carcinogenic properties and could be added to toothpastes.
https://in.bgu.ac.il/en/pages/news/Kushmaro_cavities_DIM.aspx