Proton cancer therapy trials

Jerusalem’s Hadassah Medical Center has partnered Israel’s P-Cure (see previously) and has begun trials of its focused proton radiation therapy for cancer patients. Meanwhile, Tel Aviv’s Sourasky (Ichilov) Medical Center is to install proton radiation machines from Belgium’s IBA.

Historic gene therapy operation

Doctors at Israel’s Sheba Medical Center made history with a 7-hour operation to deliver Upstaza gene therapy directly to the brain of a 4-year-old girl from India. The NIS  10 million cost per vial was the most expensive single Israeli surgery ever and was given free of charge.

Prize-winning pain relief

Israel’s TrainPain has won the Grand Prize in the American Academy of Pain Medicine (AAPM) & MIT Hacking Medicine Innovation Challenge. TrainPain uses neurotechnology to retrain sensory the brain through engaging haptic mobile games.

Reduction in Israeli skin cancer rates

In the 1990s, Israel had the 3rd highest rate of melanoma (skin cancer) per capita in the world. In 2020, Israel was not even in the top 20. Reasons include the Chacham B’Shemesh (Smart in the Sun) programs from preschool to 12th grade. Plus, annual checkups and early excision.

Award-winning skin therapy

Israel’s SofWave Medical (see previously) has won two recent international awards. At the 13th Annual NewBeauty Awards it won Best Noninvasive Cellulite Treatment. Then it won the Good Housekeeping Magazine Award for Best Anti-Aging Pro Treatment.

Israeli partnership to bio-print organs

Israeli startups Stratasys (see previously) and CollPlant (see previously) are jointly to create human tissues and organs. They will use Stratasys’ P3 bioprinter and CollPlant’s rh-Collagen-based bioinks. The first project will be to produce reconstructive implants.

Modifying gut bacteria to fight disease

Israel’s Trobix Bio is using CRISPR, phage, and synthetic biology technologies to develop precision microbiome oncology therapeutics. TBX101 counters anti-biotic resistance; TBX201 reduces chemotherapy side-effects; TBX301 tackles gut inflammation.

Relieving post-op pain

Israel’s PainReform has just completed a Phase 3 human trial of its PRF-110 post-operative pain relief. The oil-based, viscous, clear solution is deposited directly into the surgical wound bed prior to closure to provide localized and extended post-operative analgesia.

Diagnosing children with fever

The 15-min BV test from Israel’s MeMed (see previously) accurately diagnosed over 90% of bacterial versus viral infections at Israel’s Schneider Children’s Medical Center, reducing Emergency Department physician error. The study tested 287 children from 3 months to 18 years.

Schizophrenia treatment gets US approval

The US FDA has approved UZEDY (risperidone), developed for the treatment of schizophrenia by Israel’s Teva and France’s Medincell. In a Phase 3 human clinical trial, UZEDY demonstrated up to 80% reduction in risk of schizophrenia relapse versus a placebo.