Better cancer treatment
A trial of the PROphet blood test from Israel’s OncoHost (see previously) has proved its accuracy and reliability in predicting the best treatment for metastatic non-small cell lung cancer (NSCLC) patients. OncoHost has received orders from 29 US cancer centers since its 2023 launch.
Optimizing clinical trials
Israel’s PhaseV develops causal machine learning (ML) technology that optimizes clinical trial design and analysis. Its goal is to prevent bio-techs wasting money on failed or badly designed trials of new treatments. It boosts clinical trial success rates while maximizing resource and time efficiency.
Using AI to speed up gene therapy development
Israel’s mana.bio harnesses the power of AI to significantly reduce development times for new nucleic acid therapeutics and vaccines. Mana.bio produces novel lipid nanoparticles (LNPs) that deliver RNA and gene therapies to specific tissues in the body near to the liver,
Treating war-related head trauma
Israel’s Sheba Medical Center is using innovative methods to treat the complex injuries suffered by those wounded by Hamas terrorists. One example is the AI systems from Israel’s Aidoc (see previously), used to analyze brain aneurysms from gunshot wounds and rocket shrapnel.
Sports tech to heal injured soldiers
The ElectroGear device from Israel’s Healables (see previously) was designed to enhance performance and accelerate recovery among athletes. It is now being repurposed to treat pain and injuries suffered by IDF personnel. You can even help towards donating one to an Israeli soldier.
US approval for vision-correcting eye drops
The US FDA has approved the QLOSI eye drops, from Israel’s Orasis (see previously), The prescription eye drops improve farsightedness (presbyopia) for up to eight hours without impacting distance or night vision. The treatment can benefit almost two billion sufferers.
Partnering to develop IBD treatment
Israel’s Teva is partnering with France’s Sanofi (see also ) to develop and commercialize TEV 574, currently in Phase 2b clinical trials, for the anti-TL1A treatment of ulcerative colitis and Crohn's Disease, two types of inflammatory bowel disease (IBD).
Detecting too much calcium in the arteries
Israel’s Beilinson Hospital has completed a study of coronary artery calcium (CAC) levels using the HealthCCSng system from Israel’s Nanox.AI (see previously) to review routine CT-scans. High CAC patients were referred to clinics for in-depth evaluation and treatment.
Protein discovered in cancer that fools immune system
A team led by Weizmann scientists has discovered that the protein PSME4 is produced by cancer cells to stop the immune system from attacking the tumor. Reducing PSME4 levels should potentially render tumors more vulnerable to immunotherapy.
RNA molecule to treat Alzheimer’s
Researchers at Israel’s Technion Institute have engineered an RNA molecule that repairs a damaged ubiquitin-proteasome system – a possible cause of Alzheimer’s disease. A faulty ubiquitin system leads to the accumulation of toxic proteins and amyloid plaque in Alzheimer's patients.