Israel Active

Israeli startup Trisol Medical is developing a minimally invasive device that can replace a faulty tricuspid heart valve. The tricuspid valve is known as the “forgotten valve” as other bio-techs have focused efforts developing replacements for the aortic and mitral valves.

Conventional treatment of bladder stones uses a laser that causes the stone to be repelled, extending the time taken to destroy it. Israeli biotech Lumenis’ laser technology (named “Moses”) keeps the stone in place, saving time, anesthesia and money.  Nice simple video demonstrates this.

The US FDA’s oncology committee has approved CT-P10 – Teva’s monoclonal antibody biosimilar to Rituxan (rituximab) for the treatment of various forms of cancer. The development of biosimilars has the potential to increase accessibility to therapies for patients.

I reported previously on Israel’s Aidoc whose AI image software helps radiologists in fast detection of acute brain bleeds in CT scans. Aidoc’s system has now received US FDA approval and is currently in use at Israel’s Sheba Medical Center.

An Iraqi baby born with a congenital heart defect is being flown to Israel for life-saving surgery after an emergency appeal to Israel’s Interior Ministry. Baby Ahlam, from Iraqi Kurdistan, suffers from the reversal of the main arteries carrying blood from the heart.

Surgeons at Israel’s Sheba Medical Center tried to save the life a very sick 6-month old Palestinian Arab baby with a transplant of the heart donated by an Israeli Jewish child. The baby unfortunately didn’t survive.

Scientists at Israel’s Weizmann and Technion Institutes have found that each melanoma patient has a different profile of neo-antigens (mutated peptides) on their tumors. Doctors can then extract and grow the T-cells best suited to target the neo-antigens on both primary and secondary cancers.

The number of live kidney transplants performed per year in Israel has nearly tripled since 2010 mainly due to increased donations from healthy orthodox Jewish Israelis. Key to the increase is Israeli NGO Matnat Chaim (“Gift of Life”) which both publicizes the need and facilitates donation.

I reported previously on TopClosure from Israel’s IVT Medical. The innovative wound closure technique is now saving lives in China and Africa.  IVT has also developed Vcare Alpha - a suction device to remove infectious materials from wounds and accelerate wound recovery.

Israeli scientists (Hebrew University of Jerusalem and Volcani Institute) used a virus to restore the sight of a herd of Awassi sheep suffering hereditary day blindness (achromatopsia). The virus replaced a missing gene. The US FDA has now approved human trials.