Israel Active

Israel’s SpliSense (see ), is developing mRNA-altering therapies for cystic fibrosis (CF) and other genetic pulmonary diseases. SpliSense founder Professor Batsheva Kerem was part of the Hebrew University team that identified the CFTR gene and developed the CF therapy.

Israel’s Institute for Biological Research (IIBR) anticipates commencing Phase 3 of its coronavirus vaccine trials soon – probably in Argentina as 30,000 unvaccinated volunteers are required. A new trial may also be launched to test if the two-shot vaccine could be combined into a higher dose single shot.

Tel Aviv University scientists conducted the world’s first digital monitoring study to check concerns about the side effects of the SARS-Cov-2 vaccine. Almost all 160 Israelis monitored showed changes to vital signs (heart rates, blood pressure etc.). These all returned to normal 3 days later.

Scientists at Israel’s Weizmann Institute have produced the most detailed analysis yet of how SARS-Cov-2 stops cells from making the proteins needed to alert the immune system. When Covid-19 is finally detected, the immune system’s cytokine storm response is too massive.

The EXO-CD24 Covid treatment invented by doctors at Israel’s Sourasky (Ichilov) Medical Center, is about to begin Phase 2 trials in Greece on 90 patients. If successful, the treatment could be available to treat patients in India, Brazil etc. by end 2021.

Israel’s BioLineRx (see previously) has reported positive results in the Phase 3 trial of its Motixafortide treatment in combination with G-CSF for multiple myeloma. The treatment demonstrated improvement from five-fold to 14-fold compared to the control.

Dr. Aharon Bloch of Hadassah Medical Center is the first Israeli nephrologist to donate a kidney to a stranger. He made the decision after the passing of Rabbi Yeshayahu Heber, the founder of the NGO “Gift of Life” (see ) whom he treated.

Israel’s Aidoc (see ) is to provide its CT image analysis AI system for Radiology Partners, whose radiologists work in 10% of all US hospitals. Another Israeli startup DayTwo (see ) has had much success in the US with its microbiome analysis program for diabetics.

Israel’s Edocate has developed an app to help educate Health Care Professionals (HCPs) in the management of patients with chronic conditions (e.g. diabetes). Its virtual patient simulation platform allows HCPs to “learn by doing” and “learn by making mistakes” in a no-risk environment.

Researchers from Israel’s Ben-Gurion University and elsewhere have developed “molecular tweezers” to combat antibiotic-resistant bacteria. The tweezers destroy the biofilm that protects the bacteria against the immune system. Bacteria cannot develop resistance to this method of attack.