Israel Active

Scientists from Israel’s Rabin Medical Center and the Weizmann Institute studied the microbiome of 200 patients just hours after a heart attack. They found most were missing a Clostridiaceae family bacterium that was present in a control group. They are now isolating it into pill form.

The calcification of heart valves is currently resolved by transplanting a new prosthetic valve (see above). Israel’s Pi-Cardia (see previously) has been developing the Leaflex system to treat the calcification, and is currently conducting human clinical trials across Europe.

An Israeli-led team of researchers has prevented the deterioration of bioprosthetic heart valves (of animal origin). These last only 10 years due to calcification of the tissues. They used hearts from pigs that were engineered to stop expressing foreign sugars and this prevented calcification.

Scientists at Israel’s Technion Institute have found that misfolding proteins in the brain cells of ALS and Huntington’s sufferers can be corrected by other proteins already in the cell, called “chaperones”. But the cell doesn’t activate them or activates the wrong ones! New treatments are anticipated.

Although not an Israeli treatment, Israel’s Sheba Medical Center is one of the few global hospitals treating prostate cancer patients with Lutetium-177 therapy. It attaches to prostate-specific membrane antigens (PSMAs) on tumors and emits beta radiation to neutralize them.

Israel’s New Phase has developed hyperthermic treatment that kills up to 50% of metastatic cancer. In animal and human trials, iron-oxide nanoparticles, produced in a lab managed by three Druze Arab women, are injected into stage 4 cancer patients, and then heated to 45º C using RF radiation.

Israeli scientists are the first to have used hyperbaric oxygen therapy (HBOT) to reduce post-traumatic stress disorder (PTSD) symptoms. The pressurized pure oxygen treatment successfully relieved IDF veterans with treatment-resistant PTSD that had lasted for at least four years.

Ilan, the official photographer for the Hapoel Jerusalem basketball team, suffered a heart attack shortly before his team’s hoops game with Hapoel Tel Aviv. With only minutes of life left, Gal, an MDA paramedic, used a defibrillator to restart his heart. Great story for National Public Defibrillator Awareness Day.

Scientists at Israel’s Weizmann Institute discovered some remarkable actions of the immune system when faced with multiple viral or bacterial infections. Two mechanisms – innate and adaptive immunity are deployed and may change vaccines production and autoimmune disease therapies.

Researchers at Jerusalem’s Hebrew University studied 1,657 families of twins born in 2004/5. In 63 cases, one of the twins had a development delay or disability. The other twin was found to have a higher cognitive empathy than those with a normal twin.