Gene in “junk” DNA protects against ALS

Researchers at Israel’s Weizmann Institute have found a gene in the non-coding (“junk”) part of the genome that reduces five-fold the risk of developing amyotrophic lateral sclerosis (ALS). The gene IL18RAP can contain mutations that reduce inflammation in the brain.

A happy return

When United Hatzalah paramedic Leah helped deliver a baby girl in Jerusalem, she remembered the address. Three years previously it had taken 40 minutes of CPR and several shocks from a defibrillator, to restore the pulse of the baby’s father after he had suffered cardiac arrest.

Hear this

Plastic surgeons at Israel’s Galilee Medical Center attached a 3D-printed prosthetic ear to a six-year-old boy, born with microtia, to correct his birth defect. Although the ear will never be functional, the landmark operation will reduce pain, prevent future complications and is socially, aesthetically important.

Israeli space medical experiments

Enlightening article about some of the ground-breaking medical experiments performed by Israeli astronaut Eytan Stibbe aboard the International Space Station. It features the miniaturized, remotely controlled lab on a chip developed by Israel’s SpacePharma (see previously).

The world’s most protected blood bank

After 4 years’ construction, Magen David Adom has opened its new $135 million Marcus National Blood Services Center (see previously). The underground facility doubles current capacity and is shielded from terrorism, rocket attacks, earthquakes, and cyber-attack.

Phase 3 trial of oral insulin begins

Israel’s Oramed (see previously) has completed enrollment of patients for the Phase 3 trial of its oral insulin for the treatment of type 2 diabetes. Topline results of the trial are expected early 2023.

Breakthrough brain research

Israeli scientists have published a peer-reviewed paper that identifies the dendrites in the brain’s neurons as the learning center of the brain, rather than currently regarded synapses. It could help develop new types of treatments for degenerative diseases, such as Alzheimer’s and Parkinson’s.

Field hospital treated 6,000

Israel’s Kochav Meir (Shining Star) field hospital in Ukraine has closed after six weeks, having treated 6,000 patients. The hospital was originally planned to operate for one month. The initial 100 staff (80 doctors & nurses) were then replaced by new staff from Israel’s Sheba Medical Center.

No more blood shortages

Israel’s RedC Biotech is developing a process for mass-production of red blood cells for transfusions. Working with Accellta, a spin-off startup from Israel’s Technion Institute, they use stem cells from O-negative donors to mass-produce red blood cells for most humans, even without testing.

Physician cure thyself

Six years ago, Israel’s ex-Chief Scientist Dr. Orna Berry was diagnosed with cervical, ovarian, and thyroid cancer with six-months to live. Israeli startup Curesponse used genome sequencing to find her best treatment. Dr Berry is now cancer free and at the age of 72 is Google Cloud’s Director of Technology.