Israeli researchers have discovered that ALS (Lou Gehrig’s disease) patients produce less microRNA-126 than normal individuals. This allows the protein TDP-43 to build up and destroy motor neurons. When microRNA-126 is added, the process reverses. Jon Medved now has ALS.

https://www.timesofisrael.com/in-world-first-israeli-scientists-use-rna-based-gene-therapy-to-stop-als-deterioration/

https://www.nature.com/articles/s41593-025-02062-6