Search Results for: immun cancer

Immunotherapy dose reduced by a million

The NanoGhost cancer treatment targeted delivery mechanism developed by scientists at Israel’s Technion Institute is truly revolutionary (see here previously).  It enables the dose of existing immunotherapies (e.g., TRAIL) to be reduced by a millionfold, to prevent toxic side effects. … Continue reading

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Targeting cancer hotspots

A team of researchers, led by Israel’s Weizmann Institute, used algorithms to find neoantigens – “hot spots” on tumors – that provide access to current immunotherapies for multiple cancer patients. The scientists then engineered T cells from healthy individuals to … Continue reading

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Using white blood cells to fight cancer

Researchers at Tel Aviv University have discovered that a type of white blood cell (eosinophils) can be utilized to fight cancer. They have a double effect, producing destructive proteins, while at the same time summoning the immune system’s cancer-fighting T-cells. … Continue reading

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Reprogramming the immune system

This article describes the latest progress of Israel’s Immunai (see here previously) which is mapping the immune system to help develop new life-saving treatments. It acquired US-based Dropprint Genomics and has launched into development of cancer and autoimmune disease therapies. … Continue reading

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UK trials for Israeli cancer treatment test

The UK National Health Service (NHS) is to trial the blood test from Israel’s OncoHost (see here previously) that predicts how well cancer patients will respond to immunotherapy treatment. Trials will focus on patients with advanced melanoma or non-small cell … Continue reading

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Nanochip for studying cancer receptors

Scientists at Israel’s Ben Gurion University have developed a silicone nanochip that mimics an artificial cancer cell and its receptors. They can now study immune cells (e.g. lymphocytes) as they attempt to destroy the artificial cell. It reveals some surprising … Continue reading

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Cancer treatment trial extended

The Phase 1 / 2 trial of DSP107 from Israel’s KAHR Medical (see here previously) has commenced and will now be expanded to include blood cancer patients in addition to solid tumors. KAHR has received an additional investment of $5 … Continue reading

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Cancer-fighting bacteria to begin Phase 2 trials

Israel’s NeoTX Therapeutics (see here Mar 2020) has had FDA approval to begin Phase 2a human trials of its Naptumomab Estafenatox (NAP) treatment for non-small cell lung cancer. NAP binds bacteria to the tumor while activating tumor specific immune cells. … Continue reading

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The impact of the microbiome on cancer

Israel’s MyBiotics (see here previously) is to partner Hadasit – the technology transfer arm of Hadassah Medical Center, to identify gut microbiome-based cancer therapies. They will study up to 100 melanoma patients treated with PD-1/PD-L1 checkpoint inhibitor immunotherapies. https://www.timesofisrael.com/mybiotics-hadassah-to-study-impact-of-microbiome-on-cancer-therapies/

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Mutating cancer cells

Scientists at Israel’s Weizmann Institute, working with others in the Netherlands and Norway, have discovered that melanoma cells can “frameshift” to grow whilst avoiding the immune system.  The process, however, generates new peptides (short proteins) that scientists can now target … Continue reading

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