Search Results for: immun cancer

Immunotherapy to fight cancer

Israeli biotech Efranat Ltd. is developing an immunotherapy treatment approach for cancer, based on a glycoprotein named GcMAF (Globulin component Macrophage Activating Factor). Efranat has just raised $4.5 million and is conducting trials at Tel Hashomer’s Sheba Medical Center. http://jewishbusinessnews.com/2014/11/21/israels-efranat-raises-4-5-million-to-acure-cancer/

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Drug boosts immune system to fight cancer

I reported in May that Israeli biotech Compugen discovered 4 new protein variants that stimulate the immune system into targeting cancer cells. Now tests have shown that CGEN-15001T will fight carcinomas, sarcomas, melanoma and haematological cancers. http://www.globes.co.il/serveen/globes/docview.asp?did=1000721404&fid=1725

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Predicting response to cancer therapy

Immune Checkpoint Inhibitors (ICIs) are successful in 40% of cancer patients but are invasive and time-consuming. Scientists at Israel’s Technion Institute have developed a tool that predicts the response based on the metabolic activity in the immune system cells. (See … Continue reading

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Nitric Oxide for cancer

Israel’s Beyond Air (see here previously) has partnered with US-based Beyond Cancer to produce a form of immunotherapy for solid tumors known as ultra-high concentration nitric oxide (UNO). The ultra-high concentration of UNO is undergoing Phase 1 human trials. https://nocamels.com/category/news-briefs/#post-126279

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Light-activated cancer treatment gets US support

Israel’s ImPact Biotech has received Orphan treatment designation from the US FDA for its Padeliporfin VTP in Pancreatic Cancer. ImPact stands for IMmune Photo Activated Cancer Treatment and VTP is Vascular Targeted Photodynamic therapy. https://impactbiotech.com/impact-biotech-receives-fda-orphan-drug-designation-for-padeliporfin-vtp-in-pancreatic-cancer/ https://impactbiotech.com/

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007 – license to kill cancer cells

Israel’s Edity Therapeutics reprograms immune cells to recognize tumors that hide from the body’s regular immune system. Edity’s ED 007 cell therapy inflames these tumors, triggering the body’s own immune system to kill the cancer without risk of side effects … Continue reading

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US award for cancer research

The US National Foundation for Cancer Research (NFCR) honored Tel Aviv University Professor Isaac P. Witz, for his cancer research on how components of the immune system infiltrate the tumor microenvironment (TME) affecting tumor formation, progression, and metastasis. https://en-lifesci.tau.ac.il/news/2023/witz/prize https://www.jpost.com/israel-news/article-747716

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Predicting immunotherapy response

Ben-Gurion University researchers have partnered Israel’s OncoHost to develop a biosensor that safely predicts if anti-PD1 therapy may cure a specific cancer patient. The leading immune checkpoint inhibitor (ICI) therapy is invasive and other treatments may be better. (see also … Continue reading

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Weighty cancer discovery

Researchers at Israel’s Weizmann Institute have analyzed the build-up of ammonia that impairs immune cells in 50% of cancer patients. It blocks the protein regulator HNF4-alpha, causing weight loss and tumor growth. In lab tests, restoring HNF4-alpha production stops weight … Continue reading

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How the gut impacts cancer treatment

A Weizmann Institute-led international team of researchers has found how bacteria in the gut microbiome affects the body’s response to cancer immunotherapy (see also here previously). Also, patients treated with specific antibiotics had a poor response to CAR-T cancer treatment. … Continue reading

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