Wearable devices to fix mobility problems

Zuckerman Faculty Scholar Dr. Arielle Fischer runs the Fischer Biomechanics and Wearable Technology Lab at Israel’s Technion Institute. Her lab develops biomechanical tools and wearable devices to detect, prevent, and correct musculoskeletal movement disorders.

Developing treatments since 1949

Rafa Laboratories is one of Israel’s oldest pharmaceutical companies. For example, it has been supplying autoinjectors for over 30 years, for global medical conditions including seizures and now (partnering USA’s BARDA) to counter nerve agent and pesticide poisoning.

AI-driven cell therapy

Israeli-founded Somite.ai can revolutionize stem cell therapy. Its first target is Duchenne Muscular Dystrophy. When muscle stem cells are injected into an existing muscle, the muscles can rebuild and regain function. Somite will then move on to creating brown fat cells for the treatment of diabetes.

War of yeast infections

Researchers at Israel’s Weizmann Institute have discovered a benign species of yeast named “Kazachstania weizmannii” in homage to Chaim Weizmann. It prevents the spread of Candida albicans, a strain of yeast which causes candidiasis, a fungal infection responsible for around 200,000 deaths per year.

Artificial veins for successful transplants

Israel’s Bonus Biogroup (see previously) has developed microscopic biodegradable tubes that run through an engineered transplant organ, supplying a steady flow of blood. This vastly increases the viability of artificial organs and the success rate of transplant operations.

Another approach to curing Alzheimer’s

In 2023, Bar-Ilan University Prof Shai Rahimipour (see previously) worked with Canadian scientists on a peptide therapy for Alzheimer’s disease. Now he is working with Italian scientists developing nanoparticles to attack an early version of the Amyloid-beta protein.

New pathway for treating wet AMD

Prof. Ofra Benny, cofounder and CSO of Israel’s Orsight, has developed a small molecule that (in lab tests) stops the formation of excess blood vessels in the eye, thus preventing the worst effects of wet AMD. It also has prospects for use in cutting off blood supply to tumors.

Linking heart disease to cancer

Researchers at Tel Aviv University and Sheba Medical Center found that a diseased heart releases bubbles, called extracellular vesicles (sEVs). These travel through the bloodstream and promote the growth of cancer cells. Spironolactone stops sEVs and prevents cancer.

Saliva tests can prevent lifelong disabilities

Congenital cytomegalovirus (cCMV) infection causes (often lifelong) health problems for one in every 1,000 newborns in the USA. Hadassah / Hebrew Uni researchers have developed an efficient cCMV PCR saliva-based screening test for early detection & treatment.

Innovative tech gets survivor back on her feet

Neta from Kibbutz Kfar Aza was badly wounded by Hamas on Oct 7. Technion doctors created a unique orthotic device tailored specifically for Neta based on 3D scans of her leg, to aid her in walking while her ankle is unable to bear weight. It allows for adjustment as her leg heals.